Soft tissue MRgFUS treatments can be adversely affected by aberration of the focused ultrasound beam due to speed of sound differences between heterogeneous tissues. A quasi-real time beam aberration correction technique that uses an MRI derived model is presented and experimentally validated in a heterogeneous breast-mimicking phantom model. Comparison of MRgFUS sonications performed with and without phase aberration correction demonstrates that this model-based correction algorithm results in improved MRgFUS treatment efficiency and accuracy. This is shown to affect both thermal and mechanical MRgFUS applications.
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