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Abstract #1200

Multi-contrast EPI - Towards clinical application

Tim Sprenger1, Mathias Engström1, Ola Norbeck2,3, Henric Rydén2,3, Enrico Avventi2,3, Johan Berglund3, and Stefan Skare2,3

1MR Applied Science Laboratory Europe, GE Healthcare, Stockholm, Sweden, 2Karolinska University Hospital, Dept of Neuroradiology, Stockholm, Sweden, 3Karolinska Institute, Dept of Clinical Neuroscience, Stockholm, Sweden

We present an enhanced version of our multi-contrast EPI sequence which generates T1-FLAIR, T2-FLAIR, T2*w, T2w, iso-DWI, ADC images of 36 slices in 90 s. We introduce various optimization including tetrahedral diffusion encoding, different partial Fourier factors for the EPI trains and multi-echo acquisition for T2-FLAIR, T2*w, T2w, and DWI. The improved sequence is compared to our previous implementation and superior image quality is shown especially for the diffusion contrast. Finally, multi-contrast EPI patient data is shown and compared to conventional imaging sequences.

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