Abstract #1200

Multi-contrast EPI - Towards clinical application

Tim Sprenger¹, Mathias Engström¹, Ola Norbeck^2,3, Henric Rydén^2,3, Enrico Avventi^2,3, Johan Berglund³, and Stefan Skare^2,3

¹MR Applied Science Laboratory Europe, GE Healthcare, Stockholm, Sweden, ²Karolinska University Hospital, Dept of Neuroradiology, Stockholm, Sweden, ³Karolinska Institute, Dept of Clinical Neuroscience, Stockholm, Sweden

We present an enhanced version of our multi-contrast EPI sequence which generates T1-FLAIR, T2-FLAIR, T2*w, T2w, iso-DWI, ADC images of 36 slices in 90 s. We introduce various optimization including tetrahedral diffusion encoding, different partial Fourier factors for the EPI trains and multi-echo acquisition for T2-FLAIR, T2*w, T2w, and DWI. The improved sequence is compared to our previous implementation and superior image quality is shown especially for the diffusion contrast. Finally, multi-contrast EPI patient data is shown and compared to conventional imaging sequences.

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