Abstract #1301

Preliminary study of proton magnetic resonance spectroscopy with multi-echo-time for simultaneous quantification and T2 measurement of glutamate.

Chi-Hyeon Yoo^1,2, Kyu-Ho Song¹, Song-I Lim^1,2, Dong-Choel Woo², and Bo-Young Choe¹

¹Department of Biomedical Engineering, Research Institute of Biomedical Engineering, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea, ²Asan Institute for Life Sciences, Asan Medical Center, Seoul, Republic of Korea

This study presents our preliminary concept of multi-echo-time (TE) in vivo proton magnetic resonance spectroscopy (¹H MRS) for the simultaneous quantification and T2 measurement of the brain metabolites, particularly glutamate. The feasibility of the proposed method was verified by comparing metabolite concentrations to that of conventional short-TE, and T2 relaxation times to that of conventional T2 measurement. Although TE points must be further optimized, the multi-TE in vivo ¹H MRS could be used to simultaneously investigate the changes of brain metabolism and microenvironments in a scan time comparable to that of the conventional method.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.