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Abstract #1317

The Effect of  B0 and B1+ Inhomogeneities on Spinal Cord MRS

Nicholas Maurice Simard1, Aimee J Nelson2, and Michael D. Noseworthy1,3

1School of Biomedical Engineering, McMaster University, Hamilton, ON, Canada, 2Department of Kinesiology, McMaster University, Hamilton, ON, Canada, 3Department of Electrical and Computer Engineering, McMaster University, Hamilton, ON, Canada

Spinal cord 1H MR Spectroscopy (1H-MRS) is a promising method for musculoskeletal research. However, due to the spine’s anatomical location there is a significant degradation of signal quality due to magnetic field inhomogeneities, rendering most MRS approaches inaccurate. Although there has been measurement of ΔB0 in spinal cord MRS, there are no comprehensive assessments of temporal changes in B0 and B1+ relating physiological disturbances with MRS accuracy. Thus our goal was to continually measure temporal changes in B0 and B1+ during the length of a typical MEGA-PRESS scan (10min).

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