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Abstract #1389

T1-T2 correlation of site-specific changes and zone-dependent anisotropy of osteoarthritic cartilage using multi-resolution MRI

Farid Badar1 and Yang Xia1

1Physics, Oakland University, Rochester Hills, MI, United States

Topographical and zonal based studies of healthy and OA canine tibial cartilage are shown to be essential for the early detection of osteoarthritis. A high-resolution T1-T2 correlation with the low-resolution imaging of depth-dependent T2 profiles shows a more detailed and sensitive method of measuring the early sign of cartilage degradation, beneficial to human OA MRI.

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