Recent approval by the FDA for treating essential tremors has created increased interest in targeting other critical regions within the brain. Relatively low frequency 220kHz tMRgFUS system has the potential to reach off-center targets compared to the 670kHz system used for essential tremor treatment. In this work, we assess the feasibility of the 220kHz reaching targets such as the central lateral thalamus (CL) due to its role in neuropathic pain and the more laterally located temporal lope for the role it plays in temporal lobe epilepsy. Results suggest that temporal lobe interventions are possible but may require a careful optimization.
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