Abstract #1541

Tumor Metabolism, Diffusion, and Perfusion in Head and Neck Cancer: Pretreatment Multimodality Imaging with DCE-MRI, IVIM DW-MRI, 18F-FMISO PET/CT, and 18F-FDG PET/CT

David Aramburu Nunez¹, Milan Grkovski¹, Nancy Lee², Vaios Hatzoglou³, Heiko Schoder³, Ramesh Paudyal¹, Nadeem Riaz², Joseph O Deasy¹, John Humm¹, and Amita Shukla-Dave⁴

¹Medical Physics, Memorial Sloan-Kettering Cancer Center, New York City, NY, United States, ²Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York City, NY, United States, ³Radiology, Memorial Sloan-Kettering Cancer Center, New York City, NY, United States, ⁴Medical Physics and Radiology, Memorial Sloan-Kettering Cancer Center, New York City, NY, United States

The aim of this study is to understand the correlation of pretreatment quantitative imaging metrics obtained from multimodality imaging (MMI) techniques, such as DCE-MRI, IVIM DW-MRI, 18F-FMISO PET/CT, and 18F-FDG PET/CT giving us a comprehensive characterization of the tumor in head and neck cancer (HNC) patients. The results show complementary, rather than competitive, information about tumor metabolism, diffusion, and perfusion.

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