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Abstract #1671

Structural and functional brain connectivity highlights in neurosensorial profound deafness

Pedro Henrique Rodrigues da Silva1, Antonio Carlos Santos Senra Filho2, Karol Dell Ducas Senra3, Renata Ferranti Leoni1, Luiz Otavio Murta Junior2, and Antonio Carlos dos Santos3

1Department of Physics, FFCLRP, University of São Paulo, Ribeirão Preto, Brazil, 2Department of Computing and Mathematics, FFCLRP, University of São Paulo, Ribeirão Preto, Brazil, 3Department of Medical Clinics, FMRP, University of São Paulo, Ribeirão Preto, Brazil

The absence of auditory stimuli for a long period leads to modifications in brain structural and functional connectivity. However, the relationship between the brain changes and neurosensorial hearing loss is not fully clarified. In this study we considered a group of subjects with pre-lingual congenital deafness and analyzed their structural and functional connectivity. Our results suggest that auditory input deprivation not only alters the activity of sensory areas but also reshape the structural and functional organization of cognitive-related networks. These findings can be instructive to clinical practice.

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