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Abstract #1729

A 3D printed lung phantom for exploration of the limits of 19F-C3F8 ventilation imaging resolution and SNR

Adam Maunder1, Fraser Robb1,2, Madhwesha Rao1, and Jim Wild1

1POLARIS, Academic Radiology, University of Sheffield, Sheffield, United Kingdom, 2GE Healthcare Inc., Aurora, OH, United States

Fluorinated gas imaging is a complementary method to hyperpolarized gas ventilation imaging, but suffers from lower SNR by virtue of low spin density and thermal polarisation. We present a 3D printed lung phantom based on a gold standard lung ventilation scan acquired from 3He MRI used to explore the limits of fluorinated gas MR in terms of spatial resolution and SNR. Images acquired with unrealistically long imaging times for in-vivo exams were compared to lower resolution images. The results demonstrate that resolutions obtainable with in-vivo fluorinated gas imaging miss potentially important spatial variation information.

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