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Abstract #1858

Reproducibility of Myelin Water Fraction for GRASE sequences with a varying SENSE factor

Gerhard Drenthen1,2, Walter Backes1,2, Albert Aldenkamp3, and Jacobus Jansen1,2

1Department of Radiology & Nuclear Medicine, Maastricht University Medical Center, Maastricht, Netherlands, 2School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, Netherlands, 3Department of Behavioral Sciences, Epilepsy Center Kempenheaghe, Heeze, Netherlands

For myelin-water quantification to become a feasible method in a clinical setting a rapid whole brain coverage acquisition is required, as well as reproducible results. Therefore, this study aims to measure the reproducibility of the Gradient-Spin Echo (GRASE) sequence with and without utilizing parallel imaging with sensitivity coding (SENSE) to investigate the impact of the acceleration (e.g. increased SENSE factor).

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