Abstract #1858

Reproducibility of Myelin Water Fraction for GRASE sequences with a varying SENSE factor

Gerhard Drenthen^1,2, Walter Backes^1,2, Albert Aldenkamp³, and Jacobus Jansen^1,2

¹Department of Radiology & Nuclear Medicine, Maastricht University Medical Center, Maastricht, Netherlands, ²School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, Netherlands, ³Department of Behavioral Sciences, Epilepsy Center Kempenheaghe, Heeze, Netherlands

For myelin-water quantification to become a feasible method in a clinical setting a rapid whole brain coverage acquisition is required, as well as reproducible results. Therefore, this study aims to measure the reproducibility of the Gradient-Spin Echo (GRASE) sequence with and without utilizing parallel imaging with sensitivity coding (SENSE) to investigate the impact of the acceleration (e.g. increased SENSE factor).

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