Abstract #1868

Magnetic resonance angiography and venography was not useful for correcting underestimated susceptibility measurements of sub-voxel objects on quantitative susceptibility maps

Natalie M Wiseman¹, Sagar Buch², Yongsheng Chen³, E Mark Haacke^3,4, and Zhifeng Kou^3,4

¹Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, United States, ²Center for Functional and Metabolic Mapping, Robarts' Research Institute, Western University, London, ON, Canada, ³Department of Radiology, Wayne State University, Detroit, MI, United States, ⁴Department of Biomedical Engineering, Wayne State University, Detroit, MI, United States

We investigated two magnetic resonance angiography and venography (MRAV) methods for use in correcting quantitative susceptibility mapping (QSM) estimates in sub-voxel veins. An MRAV generated from an interleaved rephased/dephased gradient echo sequence (without contrast agent) suffered from low SNR in veins, whereas the contrast-enhanced T1-MRAV caused the vessels to appear larger than those in the pre-contrast images. Neither method offered a reliable correction of partial-volumed susceptibility measurements.

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