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Abstract #1869

Increased cerebral oxygen extraction fraction measured in the ischemic stroke using an asymmetric spin echo EPI approach

Yong Zhang1, Qiao Li2, Jun Zhang2, and Bing Wu3

1GE Healthcare, Shanghai, China, 2Radiology, Huashan Hospital, Shanghai, China, 3GE Healthcare, Beijing, China

The oxygen consumption by brain tissue can be measured with oxygen extraction fraction (OEF), a potential indicator of the occurrence of stroke. A single shot asymmetric spin echo (ASE) EPI sequence was implemented for OEF measurement in stroke patients. Increased OEF corresponded with the decrease blood flow in the ischemic brain region, as reported in the previous literature. ASE EPI showed the potential to provide quantitative OEF maps with good brain coverage and without the need of gas challenges. The measurement of OEF may provide a better assessment of viable brain stroke after a stroke attack for potential treatment.

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