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Abstract #1937

The fronto-parietal connectivity in freezing of gait: a left/right imbalance ?

CĂ©line Tard1, Caroline Moreau2, Romain Viard3, Christine Delmaire2, David Devos2, Pierre Lenfant2, Kathy Dujardin2, Luc Defebvre2, Arnaud Delval2, and Renaud Lopes2

1Neurology Department, Lille University Hospital Center, Lille, France, 2Lille University Hospital Center, Lille, France, 3Radiology Department, Lille University Hospital Center, Lille, France

The multimodal MRI assessment is here used to better understand the previous known parietoprefrontal networks' abnormalities in parkinsonian patients with freezing of gait. Anatomic disconnection was observed in the right prefrontal cortex in those patients and functional disconnection was major from the left one. The imbalance between left and right networks is discussed heyard the pathophysiology of freezing.

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