Meeting Banner
Abstract #2057

Identification of thalamic substructures in ultra-high b-value DWI

Nils Christoph Nuessle1, Benjamin Bender1, and Uwe Klose1

1Department for Neuroradiology, University Hospital of Tuebingen, Tuebingen, Germany

Precise implantation of deep brain stimulation devices in Parkinson, primary dystonia or epilepsy patients requires precise structural information about the thalamic region. Purpose of this study was to evaluate the capability of DWI in identifying thalamic substructures. Eight healthy volunteers underwent ultra-high b-value DWI (5000 s/mm2) at 3T. Images were denoised using total generalized variation and 7 substructures (Pulvinar and six nuclei) within the thalamus were drawn in and compared to histological atlases. In all volunteers, all seven structures could be identified due to signal intensities. High b-value diffusion weighted imaging therefore shows great potential in determining thalamic substructures.

This abstract and the presentation materials are available to members only; a login is required.

Join Here