Abstract #2058

Practical parameter setting for simultaneous measurement of CBF and ATT with Hadamard-encoded ASL: Special reference for clinical practice

Shota Ishida^1,2, Hirohiko Kimura³, Naoyuki Takei⁴, Masayuki Kanamoto¹, Yasuhiro Fujiwara⁵, Tsuyoshi Matsuda⁶, R Marc Lebel⁷, and Toshiki Adachi¹

¹Radiological Center, University of Fukui Hospital, Yoshida-gun, Japan, ²Division of Health Sciences, Graduate School of Medical Sciences, Kanazawa Unversity, Kanazawa, Japan, ³Department of Radiology, Faculty of Medical Science, University of Fukui, Yoshida-gun, Japan, ⁴Global MR applications and Workflow, GE Healthcare Japan, Hino, Japan, ⁵Department of Medical Imaging, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan, ⁶Division of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, Shiwa-gun, Japan, ⁷GE Healthcare, Calgary, AB, Canada

Hadamard-encoded ASL (H-ASL) is a time-efficient method for measuring arterial transit time (ATT). The larger encoding matrix extends the scan time, but the accuracy of the ATT with a different encoding matrix was not clarified. This study aimed to propose a practical parameter selection in H-ASL for clinical use. The ATT was not significantly different between 3 and 7 delay encodings. Cerebral blood flow (CBF) obtained with 3 delay encodings with a linear division block design was equivalent to that obtained without encoding. Three delay encodings with a linear division block design provides accurate ATT and CBF within 4 minutes.

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