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Abstract #2058

Practical parameter setting for simultaneous measurement of CBF and ATT with Hadamard-encoded ASL: Special reference for clinical practice

Shota Ishida1,2, Hirohiko Kimura3, Naoyuki Takei4, Masayuki Kanamoto1, Yasuhiro Fujiwara5, Tsuyoshi Matsuda6, R Marc Lebel7, and Toshiki Adachi1

1Radiological Center, University of Fukui Hospital, Yoshida-gun, Japan, 2Division of Health Sciences, Graduate School of Medical Sciences, Kanazawa Unversity, Kanazawa, Japan, 3Department of Radiology, Faculty of Medical Science, University of Fukui, Yoshida-gun, Japan, 4Global MR applications and Workflow, GE Healthcare Japan, Hino, Japan, 5Department of Medical Imaging, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan, 6Division of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, Shiwa-gun, Japan, 7GE Healthcare, Calgary, AB, Canada

Hadamard-encoded ASL (H-ASL) is a time-efficient method for measuring arterial transit time (ATT). The larger encoding matrix extends the scan time, but the accuracy of the ATT with a different encoding matrix was not clarified. This study aimed to propose a practical parameter selection in H-ASL for clinical use. The ATT was not significantly different between 3 and 7 delay encodings. Cerebral blood flow (CBF) obtained with 3 delay encodings with a linear division block design was equivalent to that obtained without encoding. Three delay encodings with a linear division block design provides accurate ATT and CBF within 4 minutes.

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