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Abstract #2258

Morphometric Adaptions of Rectus Femoris to Muscle Strain Revealed Through ‘Dynamic Magnetic Resonance Elastography’ (DMRE)

Michael Perrins1,2, Michiel Simons2,3, Andre Attard4, Colin Brown5, Leela Biant6, Edwin J.R. van Beek2, and Neil Roberts2

1MRC Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom, 2Edinburgh Imaging Facility, University of Edinburgh, Edinburgh, United Kingdom, 3Department of Clinical Surgery, University of Edinburgh, Edinburgh, United Kingdom, 4Department of Bioengineering, University of Strathclyde, Glasgow, United Kingdom, 5The Mentholatum Company Ltd., East Kilbride, Glasgow, United Kingdom, 6Department of Trauma & Orthopeadic Surgery, University of Manchester, Manchester, United Kingdom

Magnetic Resonance Elastography (MRE) allows for the quantification of tissue stiffness. When MRE is applied in muscle it allows for the measurement of muscle strain, with strain having an impact on structure morphology. This research investigated whether the bi-articular design of the Rectus Femoris gives an anatomical advantage in adapting to muscle strain and avoiding injury, as this is a vital muscle for movement. It was found that the mono-articular Quadriceps muscles showed significant muscle strain from loading, whereas the Rectus Femoris showed significant changes in cylindrical shape, and as expected, adapted to increased loading.

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