Resting-state fMRI (rs-fMRI) in animal is essential for studying neural networks and translational research. However, animal motion poses a major obstacle for performing rs-fMRI, and it is commonly requires anesthesia that could suppress and alter the resting-state networks (RSNs). In this work, we investigated the rat RSNs under morphine condition, and the differentiation and transition of RSNs when animal conditions were changing from isoflurane to morphine. We found that the number of RSNs was significantly increased from deep anesthesia to morphine-induced condition; the RSNs became highly specific to brain functions; and thus, RSN mapping became more reliable.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords