Abstract #2340

Resting-state fMRI reveals altered auditory and pain perception networks in patients with inflammatory bowel disease (IBD)

Faranak Heidari¹, Gilaad Kaplan², Mark Swain², and Bradley Goodyear³

¹Biomedical Engineering Graduate Program, University of Calgary, Calgary, AB, Canada, ²Department of Medicine, Snyder Institute for Chronic Diseases, University of Calgary, Calgary, AB, Canada, ³Radiology, Clinical Neurosciences, Psychiatry, The Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada

Inflammatory bowel disease (IBD) is a chronic and painful inflammatory-mediated disease of the gastrointestinal system. Recent animal model evidence suggests that cognitive deficits and mood changes experienced by IBD patients are not merely emotional reactions, but result from structural and functional changes in the brain. We used dual-regression analysis of resting-state fMRI data to identify alterations in functional connectivity in IBD patients compared to controls. Connectivity was altered with auditory and pain perception networks, which may help explain behavioural symptoms (hearing loss, pain) commonly experienced by IBD patients.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.