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Abstract #2361

Title: Self-Regulation of vmPFC Activation Using Real-Time fMRI Neurofeedback

Ahmad Mayeli1,2, Vadim Zotev1, Raquel Phillips1, Hazem Refai2, Martin Paulus1, and Jerzy Bodurka1,3

1Laureate Institute for Brain Research, Tulsa, OK, United States, 2Electrical and Computer Engineering, University of Oklahoma, Tulsa, OK, United States, 3College of Engineering, Stephenson School of Biomedical Engineering, University of Oklahoma, Tulsa, OK, United States

In this study, we have examined the feasibility of training healthy human subjects to self-regulate the hemodynamic activity of the vmPFC using real-time fMRI neurofeedback (rtfMRI-nf). Eight healthy subjects took part in experimental group with real rtfMRI neurofeedback from vmPFC and four in control group with a sham feedback from HIPS region. The results show significant vmPFC BOLD activity differences between the groups, demonstrating the feasibility of targeted modulation of the vmPFC using the rtfMRI-nf.

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