Abstract #2361

Title: Self-Regulation of vmPFC Activation Using Real-Time fMRI Neurofeedback

Ahmad Mayeli^1,2, Vadim Zotev¹, Raquel Phillips¹, Hazem Refai², Martin Paulus¹, and Jerzy Bodurka^1,3

¹Laureate Institute for Brain Research, Tulsa, OK, United States, ²Electrical and Computer Engineering, University of Oklahoma, Tulsa, OK, United States, ³College of Engineering, Stephenson School of Biomedical Engineering, University of Oklahoma, Tulsa, OK, United States

In this study, we have examined the feasibility of training healthy human subjects to self-regulate the hemodynamic activity of the vmPFC using real-time fMRI neurofeedback (rtfMRI-nf). Eight healthy subjects took part in experimental group with real rtfMRI neurofeedback from vmPFC and four in control group with a sham feedback from HIPS region. The results show significant vmPFC BOLD activity differences between the groups, demonstrating the feasibility of targeted modulation of the vmPFC using the rtfMRI-nf.

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