Abstract #2500

Abdominal and organ fat content quantification in PROFAST trial (Probiotics and intermittent fasting to improve pre-diabetes)

Dech Dokpuang¹, Rinki Murphy², Lindsay Plank², Reza Nemati¹, and Jun Lu^3,4

¹Auckland University of Technology, Auckland, New Zealand, ²University of Auckland, Auckland, New Zealand, ³School of Science, Auckland University of Technology, Auckland, New Zealand, ⁴College of Life Sciences, Shenzhen University, Shenzhen, China

The primary objective of this study was to test quantification protocols on human abdominal and organ fat data acquired using magnetic resonance (MR) imaging or spectroscopy. Liver, pancreatic, visceral and subcutaneous fat in 10 obese patients with prediabetes were measured before and after a 12-week intermittent fasting programme with daily probiotic or placebo supplementation. All participants were scanned by a Siemens 3.0T MR scanner. The quantification of fat contents was performed using ImageJ (for MRI data) and SIVIC software (for MRS data). Two methods of quantifying pancreas fat were compared.

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