Abstract #2602

Comparison of Hepatic Quantitative Susceptibility Mapping and R2* for Iron Measurement in Presence of Fat and Fibrosis; an Ex-Vivo Study

Ramin Jafari¹, Anne Koehne de Gonzalez², Yi Wang^1,3, Thanh Nguyen ³, Alexey Dimov¹, Kofi Mawuli Deh³, Zhe Liu¹, Gary Brittenham², Martin Prince³, and Pascal Spincemaille³

¹Cornell University, Ithaca, NY, United States, ²Columbia University Medical Center, New York, NY, United States, ³Weill Cornell Medicine, New York, NY, United States

Precise measurement of liver iron content (LIC) in patients with transfusional iron overload is important in iron-chelation therapy. MRI can be used as a non-invasive method to measure iron levels in the liver. Typically, R2 and R2* based methods are used for this purpose. In this work, we use human liver explants to demonstrate the degree to which steatosis and fibrosis are confounding factors for R2* and quantitative susceptibility mapping in LIC measurement.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.