This study investigated the value of multi-parametric analysis using IVIM, DKI and MR T1ρ for the diagnosis of advanced liver fibrosis. Sixteen healthy rats and fifteen rats with advanced liver fibrosis (F4 confirmed by liver pathological examination) were scanned with IVIM, DKI and MR T1ρ. IVIM derived D*, D, f, DKI derived MD, K value and MR T1ρ derived T1ρ value were compared between the above two groups. Our results showed D*, D, f and MD decreased while K value and T1ρ value increased in rats with advanced liver fibrosis. And D*, D, f, K value and T1ρ value demonstrated significant difference (P<0.05). We therefore conclude that decreased D*, D and f and increased K value and T1ρ value could be useful in the diagnosis of liver fibrosis.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords