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Abstract #2778

Physical parameterization of relaxation curves in GRE sequences

Alexey Vladimirovich Protopopov1 and Michael Bock1

1Dept.of Radiology, Medical Physics, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany

The parameter T2* is often used to describe the apparent rate of spin-spin relaxation in the presence of local magnetic field gradients, which is commonly assumed to be mono-exponential. However, the behavior of the transverse relaxation is more complex, since structural characteristics of biological tissues are encoded in the shape of relaxation curve which cannot be described by a single parameter. Several attempts have been made to introduce more accurate relaxation models. In this work we present a concept for the quantitative analysis of the relaxation curve shape in gradient-recalled echo (GRE) imaging based on physical parameters of the signal.

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