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Abstract #2899

Isotropic 3D Late Gadolinium Enhancement Imaging using 3D Patch-Based Super-Resolution

Aurelien Bustin1,2,3, Damien Voilliot3,4, Jacques Felblinger3,5,6, Laurent Bonnemains3,7, and Freddy Odille3,5,6

1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2Department of Computer Science, Technical University of Munich, Munich, Germany, 3IADI, INSERM U947 and Universite de Lorraine, Nancy, France, 4Department of cardiology, University Hospital of Brabois, Nancy, France, 5CIC-IT 1433, INSERM, Nancy, France, 6Pole Imagerie, CHRU de Nancy, Nancy, France, 7Department of Cardiac Surgery, CHU Strasbourg, Strasbourg, France

Cardiac late gadolinium enhancement (LGE) imaging has become a reference clinical tool for assessing myocardial scar and viability. Despite superior signal-to-noise-ratio of 3D LGE techniques, current 3D breath-hold acquisitions are still limited by scan time and low-resolution, especially in the through-plane direction. Consequently, most clinical protocols include three anisotropic LGE acquisitions in different views to better visualize myocardial fibrosis in different orientations. Nevertheless, assessing myocardial viability in different views remains tedious and time-consuming. In this study, we sought to achieve isotropic 3D LGE by combining low-resolution anisotropic acquisitions using a 3D patch-based super-resolution reconstruction.

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