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Abstract #2910

Simultaneous Multi-Slice Gradient Echo Spin Echo EPI (SMS-GESE-EPI) enables simultaneous cardiac T2 and T2* imaging and mapping across six slices within a single heartbeat

Maaike van den Boomen1,2, Mary Kate Manhard2, Christopher Nguyen3,4, SoHyun Han2, Kyre E. Emblem5, Riemer H.J.A. Slart6,7, Ciprian Catana2, Niek H.J. Prakken1, Bruce Rosen2, Ronald J.H. Borra6,8, and Kawin Setsompop2,9,10

1Department of Radiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 2A.A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 3Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States, 4Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 5Oslo University Hospital, Oslo, Norway, 6Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 7Department of Photonic Imaging, University of Twente, Enschede, Netherlands, 8Medical Imaging Centre of Southwest Finland, Turku University Hospital, Turku, Finland, 9Department of Radiology, Harvard Medical School, Boston, MA, United States, 10Division of Health Sciences and Technology, Harvard-MIT, Cambridge, MA, United States

Cardiac T2* and T2-based techniques suffer from variabilities introduced by acquisition over multiple heartbeats and breath holds. We demonstrate the use of a dual-echo SMS-GESE-EPI sequence that can simultaneously provide T2*- and T2-weighted images from six slice locations within a single heartbeat and breath-hold. Introduction of 5-echos also enabled dynamic T2*- and T2-mapping per heartbeat within a breath-hold. These dynamically acquired T2*- and T2-maps remained stable over ten heartbeats. Several applications might benefit from these modified GESE sequences, such as BOLD measurements and vessel architecture imaging of the myocardium.

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