Meeting Banner
Abstract #3047

GMP-grade nanoparticle imaging agent for 19F MR, photoacoustic, and fluorescence imaging

Edyta Swider1, Khalid Daoudi2, Eric van Dinther1, Alexander H. J. Staal1, N. Koen van Riessen1, Olga Koshkina1, I. Jolanda M. de Vries1,3, Chris L. de Korte2, and Mangala Srinivas1

1Tumor Immunology, Radboud Institute for Molecular Life Sciences, Nijmegen, Netherlands, 2Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, Netherlands, 3Medical Oncology, Radboud University Medical Center, Nijmegen, Netherlands

Cellular therapies hold great promise for the treatment of various diseases. Its success strongly depends on the imaging modality and cell tracking, which can be achieved by the addition of an imaging label to cells, for example in the form of nanoparticles. Here, we report on polymeric nanoparticles encapsulating perfluorocarbon and dye, which can be used for cell loading and can be detected with several imaging modalities. This will further give information about cell numbers and localization in vivo.

This abstract and the presentation materials are available to members only; a login is required.

Join Here