Abstract #3067

Dynamic Hyperpolarized 13C MRSI using the SPICE technique: A feasibility study

JaeEun Song¹, Jaewook Shin¹, Hansol Lee¹, Young-suk Choi², Chan Gyu Joo³, Ho-Taek Song², and Dong-Hyun Kim¹

¹Department of Electrical and Electronic Engineering, Yonsei University, Seoul, Republic of Korea, ²Yonsei University College of Medicine, Seoul, Republic of Korea, ³Yonsei Biomedical Science Institute, College of Medicine, Yonsei University, Seoul, Republic of Korea

In this study, we investigated the use of SPICE (SPectroscopic Imaging by exploiting spatiospectral CorrElation) technique for dynamic hyperpolarized ¹³C MRSI by in vitro phantom experiment and in vivo mouse experiment. In vitro phantom experiment, the dynamic images from SPICE were compared to the dynamic data from FIDCSI. In vivo experiment, the dynamic images were acquired in normal and high fat diet (HFD) mouse kidney.

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