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Abstract #3242

Correlation of baseline DSI based metrics with clinical motor outcomes at 6 weeks after acute ischemic stroke

Kyler K Hodgson1, Ganesh Adluru2, Lorie Richards3, Jennifer Majersik4, Nagesh Adluru5, and Edward DiBella2

1Bioengineering, University of Utah, Salt Lake City, UT, United States, 2Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, United States, 3Occupational Therapy, University of Utah, Salt Lake City, UT, United States, 4Neurology, University of Utah, Salt Lake City, UT, United States, 5Waisman Center, University of Wisconsin, Madison, WI, United States

The difference between the baseline ipsilesional and contralesional mean values in the internal capsule from Orientation Dispersion Index and Generalized Fractional Anisotropy correlate strongly with upper extremity clinical outcomes at 6 weeks. These models account for regions of crossing fibers and demonstrate improvements over DTI in using brain microstructure to make clinical judgments.

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