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Abstract #3309

MR spectroscopy of mouse spinal cord injury at 9.4 Tesla

Abdullah Ali Asiri1,2, Gary Cowin1, Marc Ruitenberg3, and Nyoman Kurniawan1

1Centre for Advanced Imaging, University of Queensland, Brisbane, Australia, 2Najran University, Najran, Saudi Arabia, 3School of Biomedical sciences, The University of Queensland, Brisbane, Australia

This study aims to measure metabolic changes in the acute and chronic stages of a mouse model of spinal cord injury (SCI) using MR spectroscopy. Animal groups consisted of sham, SCI, and SCI with an intravenous immunoglobulin (IVIG) treatment. This study showed that the NAA/Cho ratio can be used as a sensitive marker for chronic injury and testing the efficacy of IVIG to promote recovery.

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