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Abstract #3390

Contrast Preparation Pulses Robust to B1 and B0 Inhomogeneities: an Optimal Control Approach

Eric Van Reeth1, Hélène Ratiney1, Kevin Tse Ve Koon1, Michael Tesch2, Denis Grenier1, Olivier Beuf1, Steffen J Glaser2, and Dominique Sugny3,4

1CREATIS, Villeurbanne, France, 2Department of Chemistry, TUM, Munich, Germany, 3ICB, Dijon, France, 4TUM, Institute for Advanced Study, Munich, Germany

This abstract proposes an optimal control strategy for the computation of contrast preparation pulses robust to B1 (+/- 35%) and B0 (+/- 400Hz) inhomogeneities. The problem formulation allows to optimize the compromise between contrast performance and preparation time. An in vitro short-T2 enhancing contrast experiment validates the robustness superiority of the proposed preparation compared to a block pulse-based scheme, and shows a good match with simulations.

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