Abstract #3390

Contrast Preparation Pulses Robust to B1 and B0 Inhomogeneities: an Optimal Control Approach

Eric Van Reeth¹, Hélène Ratiney¹, Kevin Tse Ve Koon¹, Michael Tesch², Denis Grenier¹, Olivier Beuf¹, Steffen J Glaser², and Dominique Sugny^3,4

¹CREATIS, Villeurbanne, France, ²Department of Chemistry, TUM, Munich, Germany, ³ICB, Dijon, France, ⁴TUM, Institute for Advanced Study, Munich, Germany

This abstract proposes an optimal control strategy for the computation of contrast preparation pulses robust to B1 (+/- 35%) and B0 (+/- 400Hz) inhomogeneities. The problem formulation allows to optimize the compromise between contrast performance and preparation time. An in vitro short-T2 enhancing contrast experiment validates the robustness superiority of the proposed preparation compared to a block pulse-based scheme, and shows a good match with simulations.

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