The purpose of the experiment was to investigate differences in the connectivity between the insular cortex out of the brain areas and other brain areas and the concentration of neuro-metabolites between male adult smokers and non-smokers in their 20s so that the results can be utilized as basic data for smoking cessation programs. The Cr concentration in the right insular cortex area of non-smokers is higher than that of smokers. In addition, it could be seen that smokers had stronger connectivity between their right insular cortex area and Gyrus Right, Occipital Fusiform, and Gurus Right areas than non-smokers and that non-smokers had stronger connectivity between their left insular cortex area and the frontal role right than smokers.
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