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Abstract #3615

Paravermal sign: new MR imaging features of cerebellum in neuronal intranuclear inclusion disease

Noriko Sato1, Atsuhiko Sugiyama2, Yukio Kimura1, Yuko Saito3, and Hiroshi Matsuda3

1Radiology, National Center of Neurology and Psychiatry, Tokyo, Japan, 2Neurology, Ciba University, Chiba, Japan, 3National Center of Neurology and Psychiatry, Tokyo, Japan

Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder with characteristic high signals along the corticomedullary junction on MR DWI. However, cerebellar findings have not been fully evaluated on MRI and we reviewed them in a series of ten NIID patients. MRI results showed cerebellar atrophy (10/10), high intensity signal on FLAIR images in medial part of the cerebellar hemisphere immediately beside the vermis (paravermal area) (7/10), and in the middle cerebellar peduncle (6/10). The paravermal abnormal signals could be a clue for diagnosis of NIID even in the past MR studies in which DWI was not examined.

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