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Abstract #3638

Differential diagnosis in Parkinsonism using diffusion tensor as measured from multiple cortical regions

Fan Huang1, Sung-han Lin2, Chin-Song Lu3, Yi-Hsin Weng3, Yao-Liang Chen4, Shu-Hang Ng5, Yi-Ming Wu5, Chih-Chien Tsai1, Yi-peng Liu6, and Jiun-Jie Wang1

1Medical Imaging and Radiological Science, Chang Gung University, Taoyuan, Taiwan, 2Medical Imaging and Radiological Sciences, Chang Gung University, Taoyuan, Taiwan, 3Neurology, Chang Gung Memorial Hospital, Taoyuan, Taiwan, 4Diagnostic Radiology, Keelung Chang Gung Memorial Hospital, Keelung, Taiwan, 5Diagnostic Radiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan, 6University of Electronic Sciencee and Technology of China, School of Electronic Engineering, Chengdu, China

Parkinsonism is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The cortical parcellation algorithm was applied to evaluate the cortical involvement in the patients with PD by using diffusion tensor image. The fractional anisotropy is feasible in the brain of patients with Parkinsonism. Therefore fractional anisotropy could be a potential image based biomarker for monitoring Parkinson progression.

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