Abstract #3638

Differential diagnosis in Parkinsonism using diffusion tensor as measured from multiple cortical regions

Fan Huang¹, Sung-han Lin², Chin-Song Lu³, Yi-Hsin Weng³, Yao-Liang Chen⁴, Shu-Hang Ng⁵, Yi-Ming Wu⁵, Chih-Chien Tsai¹, Yi-peng Liu⁶, and Jiun-Jie Wang¹

¹Medical Imaging and Radiological Science, Chang Gung University, Taoyuan, Taiwan, ²Medical Imaging and Radiological Sciences, Chang Gung University, Taoyuan, Taiwan, ³Neurology, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ⁴Diagnostic Radiology, Keelung Chang Gung Memorial Hospital, Keelung, Taiwan, ⁵Diagnostic Radiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ⁶University of Electronic Sciencee and Technology of China, School of Electronic Engineering, Chengdu, China

Parkinsonism is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The cortical parcellation algorithm was applied to evaluate the cortical involvement in the patients with PD by using diffusion tensor image. The fractional anisotropy is feasible in the brain of patients with Parkinsonism. Therefore fractional anisotropy could be a potential image based biomarker for monitoring Parkinson progression.

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