Meeting Banner
Abstract #3701

Case Report: Hyperpolarized 13C Metabolic Imaging of a Castration-Resistant Prostate Cancer Patient

Casey Y. Lee1,2, Benjamin J. Geraghty1,2, Justin Y. C. Lau1,2,3, Albert P. Chen4, William J. Perks5, Masoom A. Haider6, Urban Emmenegger7,8, and Charles H. Cunningham1,2

1Medical Biophysics, University of Toronto, Toronto, ON, Canada, 2Physical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada, 3Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom, 4GE Healthcare, Toronto, ON, Canada, 5Pharmacy, Sunnybrook Research Institute, Toronto, ON, Canada, 6Medical Imaging, University of Toronto and Ontario Institute of Cancer Research, Toronto, ON, Canada, 7Sunnybrook Odette Cancer Centre and Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON, Canada, 8Institute of Medical Science, University of Toronto, Toronto, ON, Canada

The feasibility of applying hyperpolarized 13C MRI to acquire metabolic (lactate, pyruvate) images of the vertebral region of a castration-resistant prostate cancer patient was investigated in this pilot study. The lactate and pyruvate signal-to-noise ratios (SNRs) of spine, back muscle, aorta, and kidney are reported. The summary of patient’s clinical history is illustrated to aid the understanding of implications of 13C-lactate signals observed in this study.

This abstract and the presentation materials are available to members only; a login is required.

Join Here