In order to detect and characterize pulmonary metastases in small animals, a 3D UTE sequence using a hybrid radial/spiral encoding, was employed while free breathing. Due to the high contrast and the high spatial resolution (125μm isotropic), early-growing metastases (representing less than 10 voxels) were detected in mice in only 12min. In parallel, through the acceleration of the acquisition by 4, the same sequence was used to perform, for the 1st time, DCE-MRI on pulmonary metastases in mice. The new pulmonary-dedicated sequence enables to obtain either anatomical or DCE-MRI information in mice.
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