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Abstract #3976

Optimal phased-array signal combination from separate coil elements for GABA quantification at 7T

Donghyun Hong1, Seyedmorteza Rohani Rankouhi1, Jan-Willem Thielen1, and David G. Norris1,2

1Erwin L. Hahn Institute for MRI, University of Duisburg-Essen, Essen, Germany, 2Donders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, Netherlands

Hitherto, signal combination strategies from separate coil elements have been evaluated on the basis of spectral SNR improvement. This study compared various combination methods for two representative GABA measurement techniques: GABA editing and short echo time acquisitions, and investigated which signal combination method is optimal in terms of GABA quantification using LCModel.

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