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Abstract #4111

Atlas-based breathing motion correction for dynamic lung XeMRI

ADAM SZMUL1, Bartlomiej Papiez1, Ozkan Doganay2, Fergus Gleeson2,3, Daniel Bulte1, Julia A. Schnabel4, and Vicente Grau1

1Department of Engineering Science, University of Oxford, Oxford, United Kingdom, 2Department of Oncology, University of Oxford, Oxford, United Kingdom, 3Department of Radiology, University of Oxford, Oxford, United Kingdom, 4Department of Biomedical Engineering, King's College London, London, United Kingdom

In this work we propose a framework to compensate for the breathing motion for dynamic lung XeMRI (DXeV), aligning images from different breathing phases and therefore increasing the accuracy of the ventilation analysis process. We build a lung atlas, to delineate a plausible shape of the lungs in the ventilation images, which is further used to co-register all ventilation volumes in the sequence to the reference lung atlas. After applying the proposed breathing motion correction method, the tidal breathing motion has been largely compensated and all masks of ventilation volumes correspond to each other spatially.

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