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Abstract #4446

Diffusional Kurtosis Imaging for Differentiation of Additional Suspicious Lesions on Preoperative Breast MRI of Patients with Known Breast Cancer

Vivian Youngjean Park1, Sungheon G Kim2, Eun-Kyung Kim1, Hee Jung Moon1, Jung Hyun Yoon1, and Min Jung Kim1

1Radiology, Yonsei University College of Medicine, Seoul, Republic of Korea, 2Center for Advanced Imaging Innovation and Research (CAI2R), New York University School of Medicine, New York, NY, United States

We investigated the potential of diffusional kurtosis imaging (DKI) and conventional diffusion weighted imaging (DWI) for differentiation of additional suspicious lesions on preoperative breast MRI patients with known breast cancer. This study included 53 pathologically confirmed lesions larger than 10mm in 45 women with known breast cancer. DKI and DWI parameters were compared between lesions. Multiple DKI parameters showed a significant difference between benign vs. invasive breast lesions and a few differed between DCIS vs. invasive breast lesions, with high specificity. However, DKI and DWI could not distinguish DCIS from benign lesions and may have lower potential in this subgroup

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