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Abstract #4467

Depiction of Gas Flow Patterns in Pulmonary Dynamic Hyperpolarized Gas MRI

Sa Xiao1,2, He Deng1,2, Caohui Duan1,2, Junshuai Xie1,2, Xianping Sun1,2, Chaohui Ye1,2, and Xin Zhou1,2

1State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan, China, 2University of Chinese Academy of Sciences, Beijing, China

Dynamic hyperpolarized gas MRI of lung is able to visualize the dynamic changes of pulmonary morphology during the ventilation process, which provides the important information about lung physiology and pathophysiology. However, there is a lack of an effective method to depict the gas flow patterns in the whole lung. In this work, we propose a motion field calculation method based on the pulmonary gas flow properties, which can acquire the velocity and direction of gas flow. The performance of the proposed method is investigated experimentally.

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