Pulmonary disease involving lung injury (e.g. ventilator-induced lung injury, radiation-induced lung injury, interstitial lung disease) can lead to pulmonary dysfunction which may not be detectable using proton pulmonary magnetic resonance imaging or ventilation imaging with hyperpolarized noble gases. The solubility of 129Xe in biological tissues and resultant chemical shifts allow for the quantification of physiological gas exchange which hold promise for the clinical evaluation of early pulmonary dysfunction. In this work we demonstrate an approach for dissolved-phase 129Xe gas exchange imaging within a single breath-hold in healthy human volunteers.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords