The MR dispersion imaging (MRDI) has shown great promise in prostate DCE-MRI, but there still exist practical limitations due to the complex model fitting. We evaluate fitting uncertainties and errors in parameter estimation for MRDI and recently proposed modified MRDI (mMRDI). We use the time-concentration curves derived from 94 prostate cancer lesions for fitting uncertainties and errors and assess the ability to delineate between cancerous and normal prostate tissues.
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