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Abstract #4564

Movement of blood within the placenta

Simon Shah1, Nia Jones2, Lucy Edwards1, Richard Bowtell1, and Penny Gowland1,3

1Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, Nottingham, United Kingdom, 2Division of Child Health, Obstetrics and Gynaecology, School of Medicine, Nottingham, United Kingdom, 3Nottingham University Hospitals NHS Trust and University of Nottingham, NIHR Nottingham Biomedical Research Centre, Nottingham, United Kingdom

Healthy placental function requires optimum percolation of blood throughout the intervillous space to provide adequate feto-maternal exchange. This depends on blood flow from the spiral arteries and permeability of the intervillous space - both being altered in conditions leading to fetal growth restriction. This study explores the use of diffusion based MRI to visualise and depict the blood flow within the placenta and explore the underlying micro-structure, including the repeatability of the measures.

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