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Abstract #4565

Rapid single slice multidimensional fetal flow imaging with MRI

Datta Singh Goolaub1,2, Christopher Roy2, Dafna Sussman2,3,4, Mike Seed5,6, and Christopher Macgowan1,2

1Medical Biophysics, University of Toronto, Toronto, ON, Canada, 2Translational Medicine, Hospital for Sick Children, Toronto, ON, Canada, 3Biomedical Engineering, Ryerson University, Toronto, ON, Canada, 4The Keenan Research Centre for Biomedical Science, St. Michael’s Hospital, Toronto, ON, Canada, 5Division of Cardiology, Hospital for Sick Children, Toronto, ON, Canada, 6Paediatrics, University of Toronto, Toronto, ON, Canada

In this study, we demonstrate multidimensional fetal blood flow quantification, using a novel radial phase contrast sampling strategy combined with compressed sensing reconstruction. This acquisition and analysis pipeline provides high temporal resolution real-time reconstructions that enable image-based gating for subsequent CINE reconstruction. Experimental validation of gating and flow quantitation are presented from an adult volunteer. Preliminary results in two human fetuses show the feasibility of this novel strategy for multidimensional fetal flow in imaging in a single slice.

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