Abstract #4565

Rapid single slice multidimensional fetal flow imaging with MRI

Datta Singh Goolaub^1,2, Christopher Roy², Dafna Sussman^2,3,4, Mike Seed^5,6, and Christopher Macgowan^1,2

¹Medical Biophysics, University of Toronto, Toronto, ON, Canada, ²Translational Medicine, Hospital for Sick Children, Toronto, ON, Canada, ³Biomedical Engineering, Ryerson University, Toronto, ON, Canada, ⁴The Keenan Research Centre for Biomedical Science, St. Michael’s Hospital, Toronto, ON, Canada, ⁵Division of Cardiology, Hospital for Sick Children, Toronto, ON, Canada, ⁶Paediatrics, University of Toronto, Toronto, ON, Canada

In this study, we demonstrate multidimensional fetal blood flow quantification, using a novel radial phase contrast sampling strategy combined with compressed sensing reconstruction. This acquisition and analysis pipeline provides high temporal resolution real-time reconstructions that enable image-based gating for subsequent CINE reconstruction. Experimental validation of gating and flow quantitation are presented from an adult volunteer. Preliminary results in two human fetuses show the feasibility of this novel strategy for multidimensional fetal flow in imaging in a single slice.

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