Diffusion MRI (dMRI) has the potential to assess placental microstructure and microcirculation in-vivo, and hence provide insight into conditions such as fetal growth restriction and pre-eclampsia. The utility of dMRI data depends heavily upon the choice of b-values and gradient directions, although these choices have to be weighed against scanning time restrictions. To address these issues, we developed an organ-specific, data-driven, clinically-viable protocol for placental dMRI. This optimised protocol compares favourably with a naive protocol of comparable scan time.
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