Abstract #4593

Feasibility of Renal ASL in a Paediatric Cohort with Impaired Renal Function

Fabio Nery¹, Enrico De Vita^2,3, Chris A Clark¹, Isky Gordon¹, and David L Thomas³

¹Developmental Imaging and Biophysics Section, UCL Great Ormond Street Institute of Child Health, London, United Kingdom, ²National Hospital for Neurology and Neurosurgery, Lysholm Department of Neuroradiology, London, United Kingdom, ³UCL Institute of Neurology, Department of Brain Repair and Rehabilitation, London, United Kingdom

Arterial Spin Labelling (ASL) allows for non-invasive measurements of tissue perfusion. As such, it presents an attractive alternative to contrast-enhanced based methods for quantification of renal perfusion, particularly in populations with impaired renal function. In this work, we assess the feasibility of ASL in a paediatric cohort with severe kidney disease by combining a robust acquisition scheme with an optimised retrospective motion correction approach.

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