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Abstract #4593

Feasibility of Renal ASL in a Paediatric Cohort with Impaired Renal Function

Fabio Nery1, Enrico De Vita2,3, Chris A Clark1, Isky Gordon1, and David L Thomas3

1Developmental Imaging and Biophysics Section, UCL Great Ormond Street Institute of Child Health, London, United Kingdom, 2National Hospital for Neurology and Neurosurgery, Lysholm Department of Neuroradiology, London, United Kingdom, 3UCL Institute of Neurology, Department of Brain Repair and Rehabilitation, London, United Kingdom

Arterial Spin Labelling (ASL) allows for non-invasive measurements of tissue perfusion. As such, it presents an attractive alternative to contrast-enhanced based methods for quantification of renal perfusion, particularly in populations with impaired renal function. In this work, we assess the feasibility of ASL in a paediatric cohort with severe kidney disease by combining a robust acquisition scheme with an optimised retrospective motion correction approach.

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