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Abstract #4595

Tri- and Biexponential Diffusion Analyses of the Kidney: Effect of Respiratory Controlled Acquisition on Measurement Accuracy and Repeatability of Diffusion Parameters

Yuki Koshino1, Naoki Ohno2, Tosiaki Miyati2, Naoki Hori1, Yukihiro Matsuura1, and Toshifumi Gabata3

1Department of Radiological Technology, Kanazawa University Hospital, Kanazawa, Japan, 2Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan, 3Department of Radiology, Kanazawa University Hospital, Kanazawa, Japan

To investigate the effect of respiratory-controlled acquisition on intravoxel incoherent motion analysis in the kidney, we compared the fitting accuracy and repeatability of diffusion parameters with tri- and biexponential models among three different methods, ie., respiratory triggering, abdominal belt, and free breathing. Respiratory triggering shows better fitting accuracy and repeatability of tri- and biexponential diffusion parameters compared with free breathing. Moreover, abdominal belt can improve the measurement repeatability even with free breathing.

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