Abstract #4595

Tri- and Biexponential Diffusion Analyses of the Kidney: Effect of Respiratory Controlled Acquisition on Measurement Accuracy and Repeatability of Diffusion Parameters

Yuki Koshino¹, Naoki Ohno², Tosiaki Miyati², Naoki Hori¹, Yukihiro Matsuura¹, and Toshifumi Gabata³

¹Department of Radiological Technology, Kanazawa University Hospital, Kanazawa, Japan, ²Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan, ³Department of Radiology, Kanazawa University Hospital, Kanazawa, Japan

To investigate the effect of respiratory-controlled acquisition on intravoxel incoherent motion analysis in the kidney, we compared the fitting accuracy and repeatability of diffusion parameters with tri- and biexponential models among three different methods, ie., respiratory triggering, abdominal belt, and free breathing. Respiratory triggering shows better fitting accuracy and repeatability of tri- and biexponential diffusion parameters compared with free breathing. Moreover, abdominal belt can improve the measurement repeatability even with free breathing.

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