Abstract #4656

Frequency preference and tuning width dependent intrinsic functional connectivity within and across cortical depths in the human auditory cortex

Pu-Yeh Wu¹, Ying-Hua Chu¹, Jo-Fu Lotus Lin¹, Shang-Yueh Tsai², Wen-Jui Kuo³, and Fa-Hsuan Lin^1,4

¹Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan, ²Institute of Applied Physics, National Chengchi University, Taipei, Taiwan, ³Institute of Neuroscience, National Yang Ming University, Taipei, Taiwan, ⁴Department of Neuroscience and Biomedical Engineering, Aalto University, Espoo, Finland

This study revealed the frequency preference as well as tuning width dependent intrinsic functional connectivity (iFC) within and across cortical depths in the human auditory cortex. We demonstrated that both the within-depth and cross-depth feature dependent iFC have a higher selectivity in the core than noncore region as we moved from superficial to deep cortical depths. We also found that the selectivity of cross-depth feature dependent iFC decreases when two cortical depths were farther away from each other. Taken together, our findings provide the direct evidence of a cortical depth specific feature dependent iFC in the human auditory cortex.

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