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Abstract #4668

Functional Connectivity changes during Real-time fMRI based Neuro-rehabilitation of post-stroke Aphasic Patients.

Sujesh Sreedharan1, Arun K. M.1, Sylaja P. N.2, Ranaganatha Sitaram3, and Kesavadas C.1

1Imaging Sciences and Interventional Radiology, SCTIMST, Trivandrum, India, 2Neurology, SCTIMST, Trivandrum, India, 3Department of Psychiatry and Division of Neuroscience, Pontificia Universidad Católica de Chile, Santiago, Chile

Recovery from stroke to lead an improved life is one of the most sought after rehabilitation programs around the globe. Various factors are involved in the process of restoration of an impaired function. The study examined the functional network disruption due to stroke and the network changes happening during the real-time fMRI based neurofeedback training for aphasic stroke survivors to retrain the language areas. The results show that though the contralateral hemisphere for test group has strong connections when compared with controls, and with training the ipsilateral connections are strengthened and are recovering through alternate connections.

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