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Abstract #4738

Comparison of different multi-fat peak models for the assessment of hepatic iron and fat

Christian Kremser1, Michaela Plaikner1, Heinz Zoller2, Werner Jaschke1, and Benjamin Henninger1

1Dept. of Radiology, Medical University of Innsbruck, Innsbruck, Austria, 2Dept. of Internal Medicine, Medical University of Innsbruck, Innsbruck, Austria

The evaluation of hepatic iron and fat by MR techniques is of increasing interest for clinical routine. The purpose of our study was to investigate the influence of different multi-peak fat models on the obtained R2*, PDFF and goodness of fit values in patients with suspicion of diffuse liver disease. It is shown that the use of multi-peak fat spectrum modeling is highly recommended for accurate quantification of R2* and PDFF . A 6-peak model resulted in the best goodness of fit. The use of a higher number of peaks seems to offer no additional advantage.

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