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Abstract #4819

Motor recovery after initial severe stroke: confronting kinematics with brain activations

Liesjet E.H. van Dokkum1,2, Isabelle Laffont2, Denis Mottet3, Jerome Froger4, Alain Bonafe5, Nicolas Menjot-de Champfleur1, and Emmanuelle le Bars1

1Division of interventional Neuroradiology, I2FH, Gui de Chauliac, Montpellier University Hospital, Montpellier, France, 2Physical Medicine and Rehabilitation, Lapeyronie, Montpellier University Hospital, Montpellier, France, 3EuroMov, University of Montpellier, Montpellier, France, 4Physical Medicine and Rehabilitation, le Grau du Roi, Nimes University Hospital, Nimes, France, 5Division of interventional Neuroradiology, Gui de Chauliac, Montpellier University Hospital, Montpellier, France

To maximize motor recovery of the upper-limb post-stroke, rehabilitation should be adapted to the individual patient. This requires the identification of motor recovery markers in relation to corresponding brain activations. During elbow flexion/extension, kinematic analysis was confronted with corresponding fMRI activations, comparing 21 participants post-stroke with 13 controls. This provided insight into the underlying functioning and organisation of motor control, switching between ‘automatic’ feed-forward and ‘conscious’ feedback control. Post-stroke, the latter strategy was applied with an additional role for visualisation and the contralesional hemisphere, whereby different kinematic profiles were related to different brain activations, opening doors to personalized rehabilitation.

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